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MK-677 (Ibutamoren) for Sale at Chemyo

This is the Chemyo research reference for MK-677 Ibutamoren: what the compound is, its molecular identity, the formats in stock and the published batch testing. MK-677 is supplied for research use only; nothing on this page is dosing, administration or clinical guidance.

What is MK-677?

MK-677, also published as ibutamoren (MK-0677, L-163,191), is an orally active, non-peptide agonist of the ghrelin receptor (GHSR-1a). It was developed by Merck in the 1990s as a small-molecule alternative to injectable growth-hormone secretagogue peptides, and its research interest comes from its ability to stimulate pulsatile growth hormone release and raise circulating IGF-1 in study subjects.

Ibutamoren was taken into clinical studies on growth-hormone deficiency, age-related frailty and recovery after hip fracture, but it has never been approved as a medicine. Researchers usually compare it with peptide secretagogues because it shares their receptor target while being a non-peptide spiro-piperidine molecule, which is why it is stable enough to be supplied as a liquid solution or as a dry powder.

Molecular identity

CAS number 159752-10-0
Molecular formula C27H36N4O5S
Molar mass 528.66 g/mol
Synonyms Ibutamoren, MK-0677, L-163,191, Nutrobal
Research class Non-peptide growth hormone secretagogue, ghrelin receptor agonist

Where to buy MK-677 for research

Searches for where to buy MK677 turn up many listings with no batch data. At Chemyo every lot of MK-677 below has its identity, purity and, for solutions, concentration results published, so you can check the material before you order it.

Browse all SARM solutions, research powders and value packs.

Quality control

Every batch is independently tested: FTIR for identity, HPLC for purity and, for solutions, a separate concentration assay. Reports are listed by batch number in the Chemyo lab reports library, and our quality control process explains each step. To check a certificate yourself, see how to read a SARM COA.

MK-677 FAQ

Is MK-677 the same compound as ibutamoren?

Yes. MK-677 is the original Merck development code and ibutamoren is the international non-proprietary name; MK-0677 and L-163,191 are other codes for the same molecule (CAS 159752-10-0).

Is MK-677 a SARM or a peptide?

Neither. It is a non-peptide ghrelin-receptor agonist (growth hormone secretagogue). It is often grouped with SARMs by vendors, but it does not act on the androgen receptor.

Which MK-677 formats does Chemyo stock?

A 25 mg/ml liquid solution in 50 ml and a 1 g research powder, plus value packs that pair MK-677 with RAD-140, MK-2866, YK-11, LGD-4033 or Andarine.

Is MK-677 approved for human use?

No. Ibutamoren is an investigational compound with no approved medical indication. Chemyo supplies it strictly for laboratory research.

Related research references

Compliance: all Chemyo products are supplied for laboratory research only and are not for human or veterinary use. Read the terms and conditions before ordering.